Nerepis Lodge can be reached by crossing the border at Calais, Maine - St. Stephen, New Brunswick, following No. 1 Highway about 60 Miles (100Km) to Saint John. Turn North on Highway No. 7 towards Fredericton for about 15 miles, taking the Westfield Exit and turning right on Highway No.102 (Exit #80) to Public Landing. There you turn left on to Cheyne Settlement Road and go about 2½ miles to the Lodge.

Transportation can be arranged from either Fredericton or Saint John airports which are about forty miles from the Lodge.